Immunological Challenges in Vascularised Composite Allotransplantation
نویسندگان
چکیده
منابع مشابه
Composite Tissue Allotransplantation Immunology
Composite tissue allotransplantation (CTA) is an option recently introduced for major reconstruction of tissue defects. Since announcements of successful hand, larynx, knee, muscle, nerve, abdominal wall and, most recently, partial face transplantation, CTA has become one of the techniques used by plastic and reconstructive surgeons [1]. Clinical success in CTA is the culmination of progress in...
متن کاملComposite tissue allotransplantation.
Composite tissue allotransplantation (CTA) recently took its first steps in the clinical arena in 1998 with the successful hand transplant performed in Lyons, France. That single operation represented a culmination of many years of laboratory research in multiple fields involving integumentary/musculoskeletal transplantation. Here we review the prerequisite developments in the field of immunolo...
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Reconstruction of severe composite defects of the face is challenging for reconstructive surgeons. Despite several reconstructive techniques, the functional and aesthetic results of these patients are not acceptable. As a major organ, face, has an utmost importance in daily life. The specific characteristics of face require not a reconstruction, but a replace with same tissue. With the evolutio...
متن کاملSplit Rejection in Vascularized Composite Allotransplantation
INTRODUCTION Graft monitoring following vascularized composite allotransplantation (VCA) relies primarily on serial skin biopsy. However, given that VCA comprised multiple tissue types, skin biopsy may not accurately reflect rejection in other transplanted tissue. METHODS A review of the literature on episodes of both acute and chronic rejection following VCA was completed. Special attention ...
متن کاملShock Wave Treatment in Composite Tissue Allotransplantation
INTRODUCTION Composite tissue allotransplantation is a newly emerged field of transplantation. Shock wave technology has already been used in the treatment of urologic and orthopedic disorders. Recent studies demonstrated a suppression of the early proinflammatory immune response. METHODS 50 allogeneic hindlimb transplantations were performed on rats in 5 different groups. Group A (n = 10), (...
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ژورنال
عنوان ژورنال: Current Transplantation Reports
سال: 2015
ISSN: 2196-3029
DOI: 10.1007/s40472-015-0073-6